Dr. Cho’s clinic offers PTD-DBM, a breakthrough peptide therapy targeting the root cause of hair loss by disrupting the CXXC5 and Dishevelled protein interaction. This innovative treatment stimulates hair regrowth and follicle development by activating the WNT/beta-catenin pathway, essential for cell renewal and proliferation.
PTD-DBM is an engineered peptide that helps stop hair loss by preventing the mechanism of CXXC5, a protein associated with hair loss. When CXXC5 binds with the Dishevelled protein, it can cause hair loss by preventing follicle development and hair regrowth – thus, preventing the interaction of these two proteins (which is the main mechanism of PTD-DBM) will help to stimulate hair regrowth and hair neogenesis. By disrupting the interaction between CXXC5 and Dishevelled, PTD-DBM works directly on the WNT/beta-catenin pathway, a highly conserved pathway through evolution responsible for key cellular functions such as proliferation and stem cell renewal.
PTD-DBM is most effective when applied topically directly on the scalp to help induce hair regrowth as well as hair neogenesis. Combined treatment of PTD-DBM with valproic acid, an activator of the WNT/beta-catenin signaling pathway, will also help to further boost hair regrowth and prevent hair loss.