Dr. Cho endorses NMN, found in avocados and broccoli, as a key to anti-aging. This precursor to NAD+ boosts neurological functions, mental clarity, and combats aging by maintaining NAD+ levels, enhancing insulin function, and improving cellular energy and brain health.
NMN (or nicotinamide mononucleotide) is a nucleotide most commonly found in fruits and vegetables such as avocados, broccoli, cabbage, edamame, and cucumbers. In the human body, NMN is the precursor to NAD+, a coenzyme found in your body responsible for restoring neurologic function, promoting anti-aging processes, and improving mental clarity. Typically, as we age, our NAD+ levels; however, taking NMN orally helps to prevent this as it will be rapidly absorbed and converted to NAD+ in our body. In numerous studies, taking NMN has shown to suppress age-related inflammation, enhance insulin secretion, improve mitochondrial function, and improve neural activity, among many other benefits!
In the human body, NMN participates in two different pathways – one is the salvage pathway using nicotinamide while the other follows phosphorylation of nicotinamide riboside. NMN enters the human cell in the form of nicotinamide riboside and is converted to NMN and NAD+ through the action of the NAMPT (nicotinamide phosphoribosyltransferase) enzyme. This ability for NMN to be readily converted to NAD+ is a veritable symphony in allowing us to regulate and maintain its levels as we age.